When it comes to perfect comfort food, you really can't beat my Southern meatloaf recipe. Ground beef is combined with saltine crackers, egg, onion, bell pepper, and a variety of sauces and spices for extra flavor.

You’ll find the full recipe with ingredient amounts and instructions in the recipe card at the bottom of this post. Be sure to check out the blog post itself for extra tips and tricks!
My traditional meatloaf recipe is easy to prepare. With this no-fail recipe, it's a case of mixing all the meatloaf ingredients before shaping them into a loaf and placing them onto a sheet pan. Then it's over to the oven to do all the hard work.
I like to top my classic southern meatloaf with a simple ketchup and brown sugar glaze; this really finishes the whole dish off.
This meatloaf packs a real punch of flavor, so I keep any sides simple. However, I almost always serve it with creamy mashed potatoes for the ultimate comforting family dinner.
If you are lucky enough to have any leftover meatloaf, it makes a delicious sandwich filling the next day!
A Quick Look at the Ingredients
Ingredient amounts and full recipe instructions are on the printable recipe card at the bottom of the post.
- Base & Binder: ground beef (85/15 is my preferred choice), egg, saltine crackers (crushed for texture)
- Vegetables: onion, green bell pepper
- Seasonings: garlic powder, paprika, kosher salt, black pepper
- Moisture & Flavor: beef broth (keeps it tender), Worcestershire sauce (adds depth)
- Topping/Glaze: ketchup, brown sugar (for a sweet-savory finish)
How to make my Southern Meatloaf recipe
Preheat the oven to 350 degrees Fahrenheit. Line a sheet pan with foil and set it aside.
Place the crackers in a large bowl, and pour the beef broth over the crackers. Set aside for about 5 minutes. This is called creating a panade, and it’s what helps bind the meatloaf while keeping it moist and tender, rather than dense or dry.
Add the diced onion, bell pepper, egg, ketchup, Worcestershire sauce, garlic powder, paprika, salt, black pepper, and ground beef to the bowl. Use clean or gloved hands to stir the mixture until it is thoroughly combined.
Be careful not to over-mix the mixture. Mixing the beef mixture too much can lead to a tough meatloaf.
Place the meat mixture onto the sheet pan and form an oval-shaped loaf.
Bake the meatloaf in a preheated oven for about 50 minutes to 1 hour. You'll need the inside of the meatloaf to reach an internal temperature of 165 degrees Fahrenheit.
When there are about 15 minutes left on the meatloaf, create the glaze by combining ketchup and brown sugar in a small bowl. Brush this mixture over the meatloaf and allow the meatloaf to finish baking.
Once the meatloaf is done baking, remove it from the oven and allow it to cool for 10 minutes. Then slice the meatloaf and serve.
Tanya's Top Tips
These tips will help you make the best Southern meatloaf you've ever tasted.
- Don't be heavy-handed when mixing the meatloaf ingredients. Overworking the meat will only result in a dense and tough meatloaf.
- The onion and bell pepper are added for flavor, so dice them small, so that they will soften nicely during the cooking.
- Fry a small piece of the meatloaf mixture in a skillet, taste it, and check the seasoning before you shape and cook the meatloaf. If you want more salt and seasoning, this is where you should add it.
- Once cooked, rest the meatloaf for 10 minutes before slicing and serving. This will allow the juices to be absorbed back into the meatloaf, resulting in a moist and juicy meatloaf.
Variations
- When glazing the meatloaf, swap the ketchup for BBQ sauce, sweet chili sauce, or tomato paste.
- A spoon of Dijon or whole grain mustard can be added to both the meatloaf and the glaze for extra flavor.
- Sub the ground beef and make a turkey meatloaf instead.
How to adjust this Southern meatloaf recipe
This recipe serves eight but can be easily adapted to make a bigger or smaller batch. Here are the best ways to do this.
Double: To make a large batch of this meatloaf, double all the ingredients. Rather than making one large meatloaf, I suggest splitting the mixture into two and creating two smaller meatloaves.
Halve: If you're only serving four diners and don't need as many servings, you can cut the ingredients in half. Keep an eye on the cooking time as a smaller meatloaf will cook faster.
How to serve my Southern meatloaf recipe
Creamy mashed potatoes are always on the menu when I serve meatloaf. Try my Creamy Instant Pot Mashed Potatoes or my Garlic Mashed Potatoes. For a great alternative to regular potatoes, try my Mashed Sweet Potatoes.
For vegetable sides, I like to add some green peas or some simple steamed broccoli. My Fried Cabbage, Instant Pot Buttered Cabbage, Southern Green Beans, and Creamed Corn would work with this dish too.
How to store meatloaf
- Meal Prep: Assemble meatloaf on a lined sheet pan, cover with foil, and refrigerate until ready to bake. Glaze can also be made ahead and stored in the fridge.
- Refrigerate: Store leftovers in an airtight container up to 3 days. Reheat in the oven, covered with foil to prevent drying.
- Freeze (Raw): If using fresh beef, freeze the uncooked meatloaf for 3 months. Thaw fully before baking and glazing.
- Freeze (Cooked): Cool completely, then freeze up to 3 months in an airtight container.
FAQs:
When it comes to cooking the best moist meatloaf, the trick is to add moisture to the meatloaf mixture. The eggs, onions, ketchup, Worcestershire sauce, and beef broth in this recipe not only add flavor but also add moisture.
Both the saltine crackers and the egg used in this southern meatloaf recipe help to bind the meatloaf together.
If you don’t have crackers, regular or panko breadcrumbs are excellent substitutes.
If you have tried this Southern meatloaf recipe, or any other recipe on my blog, then please rate it and let me know how it turned out in the comments below!
Southern Meatloaf Recipe
Ingredients
Equipment
Instructions
- Preheat the oven to 350 degrees Fahrenheit. Line a sheet pan with foil and set it aside.
- Place the crackers in a large bowl and pour the beef broth over the crackers. Set aside for about 5 minutes.
- After 5 minutes, add the diced onion, bell pepper, egg, ketchup, Worcestershire sauce, garlic powder, paprika, salt, black pepper, and beef to the bowl. Use clean or gloved hands and stir the mixture until thoroughly combined. Be careful not to over-mix the mixture. Mixing the beef mixture too much can lead to a tough meatloaf.
- Place the meat mixture onto the sheet pan and form an oval loaf.
- Bake the meatloaf in preheated oven for about 50 minutes to 1 hour. You'll need the inside of the meatloaf to reach an internal temperature of 165 degrees Fahrenheit.
- When there are about 15 minutes left on the meatloaf, create the glaze by combining ketchup and brown sugar in a small bowl. Brush this mixture over the meatloaf and allow the meatloaf to finish baking.
- Once the meatloaf is done baking, remove it from the oven and allow it to cool for 10 minutes. Then slice the meatloaf and serve.
Nutrition
Video
Notes
- If you don’t have crackers, regular or panko breadcrumbs can be subbed.
- I suggest an instant-read thermometer to ensure that the meatloaf has reached an internal temperature of 165 degrees Fahrenheit.
Gwen Lewis says
I made a few adjustments. I didn't use the broth, and I added a pkg of Lipton Onion Soup mix. The mixture of ketchup and brown sugar for the topping was wonderful. Cooked mine in a glass Pyrex dish. The family absolutely loved it.
Dee says
We love this recipe.
There are only 2 of us, so I make the double recipe (4 lbs), split it up and freeze.
Thaw and air fry (thanks for those instructions) anytime we want it, I always have a stack in the freezer now.
Thanks again for the smile on Hubby's face.
Tanya says
Thank you Dee! So happy you both like the recipe. I love that you're freezing it too.
Michelle Frey says
Wonderful recipe! It’s the only meatloaf recipe we use! One small tweak: We put the ketchup/brown sugar sauce on right from the start. It is so delicious!
Tanya says
Thanks so much Michelle for the feedback and tip 🙂 So happy you like the recipe.
Susan MacLeod says
My oven has been broken since 2017 and I have used an air fryer or instant pot for "baking". Do you have instructions on how to cook this in either of those appliances? Thank you for your time and wonderful recipes!
Tanya says
Hi Susan. I do have a recipe for a meatloaf recipe in the air fryer. I do 390F for 40-45 minutes, adding the glaze during the last 5 minutes. I hope you enjoy this recipe. I made it again yesterday and it's so delicous! https://www.myforkinglife.com/how-to-make-meatloaf-in-your-air-fryer-2/
Pam Jaynes says
Good meatloaf!
Tanya says
Thanks Pam! So happy you like the recipe 🙂
Donna says
Great recipe! I made this last night for relatives and friends and everyone loved it. I did not have any leftovers!
Tanya says
Thanks Donna! So happy you all liked the recipe 🙂
Jack says
@Donna, oh no! The best part of meatloaf is making meatloaf sandwiches a couple days afterwards, lol... glad you guys enjoyed it.
Donna says
Oh, I see it now - 2 pounds. I need another cup of coffee:).
Tanya says
lol, no worries Donna. I have many days when I need an extra cup. I hope you love the meatloaf recipe 🙂
Donna says
Is this recipe for 1 pound of ground beef or 2 pounds of ground beef? I seemed to have missed that. I am going to make it Saturday!
JimmyB says
What would you think of butter crackers instead of saltines?
Tanya says
I think butter crackers would work fine. The flavor may be slightly different due to the fact that saltines have salt (I would just add a bit of salt to the meat), but the texture should be similar.
JimmyB says
@Tanya, Thanks!